Expression profile of AZF genes in testicular biopsies of azoospermic men

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Expression profile of AZF genes in testicular biopsies of azoospermic men.

BACKGROUND The Y-chromosome AZF regions include genes whose functions and specific roles in spermatogenesis have not been fully clarified. This study investigated the expression of several AZF (USP9Y, DDX3Y/DDX3Yt1, EIF1AY and PRY) and USP9X transcripts in testicular biopsies of 89 azoospermic men who had been classified by histology and cytology assessments. METHODS Expression was analysed b...

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Macrophages and Leydig Cells in Testicular Biopsies of Azoospermic Men

A number of studies have indicated that testicular macrophages play an important role in regulating steroidogenesis of Leydig cells and maintain homeostasis within the testis. The current paper deals with macrophages (CD68 positive cells) and Leydig cells in patients with nonobstructive azoospermia (NOA). Methods employed included histological analysis on semi- and ultrathin sections, immunohis...

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Histopathologic patterns of testicular biopsies in infertile azoospermic men with varicocele.

In azoospermic infertile men with varicocele, testicular biopsy revealed histopathologic patterns that varied from disorganized spermatogenesis with low or moderate sperm scores to early (primary spermatocytes stage) or late (spermatid stage) arrested spermatogenesis or germ cell aplasia and Sertoli cells only. Diagnostic testicular biopsy can be helpful for accurate management of azoospermic i...

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Testicular Sperm Retrieval in Azoospermic Men

Peter Pantke , Thorsten Diemer , Marcelo Marconi , Martin Bergmann , Klaus Steger , Hans-Christian Schuppe , Wolfgang Weidner * Department of Urology and Pediatric Urology, University of Giessen, Giessen, Germany b Institute of Veterinary Anatomy, Histology and Embryology, University of Giessen, Giessen, Germany Centre for Dermatology and Andrology, University of Giessen, Giessen, Germany e u r...

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Testicular Biopsies of Azoospermic Men at The Lagos State University Teaching Hospital

Objectives: This study was conducted to evaluate the histological findings from testicular biopsies in azoospermic men seen at the Lagos State University Teaching Hospital, Ikeja Lagos, Nigeria. Patients and Methods: A retrospective study of testicular biopsies of azoospermic men who presented to our institution from 2005 to 2006 was performed. The patient’s age, type of infertility and histopa...

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ژورنال

عنوان ژورنال: Human Reproduction

سال: 2006

ISSN: 1460-2350,0268-1161

DOI: 10.1093/humrep/del341